Platelet Indices in Uterine Leiomyoma Compared with other Major Gynecological Diseases

Covali, Roxana and Socolov, Demetra and Pavaleanu, Ioana and Carauleanu, Alexandru and Socolov, Razvan (2020) Platelet Indices in Uterine Leiomyoma Compared with other Major Gynecological Diseases. Journal of Advances in Medicine and Medical Research, 32 (24). pp. 164-176. ISSN 2456-8899

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Abstract

Aims: The aim of this study was to determine whether platelet indices are of value when diagnosing uterine leiomyomas.

Study Design: Prospective study.

Place and Duration of Study: Elena Doamna Obstetrics and Gynecology University Hospital, Iasi, Romania, between January 2017 and December 2017.

Methodology: In this study 98 patients were selected from 140 consecutive screened patients and operated upon; 53 of the operated-on patients had uterine leiomyoma (Group 1) and 45 had severe non-leiomyoma gynecological disease (Group 2). Complete blood count, just before the intervention was studied.

Results: The RDW-CV, PLT and PCT values were significantly higher (P = .017, P = .05, P = .001, respectively) in leiomyoma patients, whereas WBC, RBC, MPV, PDW, P-LCR, NLR, PLR were not significantly different between the 2 groups. The inflammatory indices WBC, NLR and PLR were not significantly higher in leiomyoma patients compared with non-leiomyoma patients, despite the fact that leiomyoma also has an inflammatory cause. Although leiomyomas were accompanied by acute or chronic blood loss, only RDW-CV was significantly higher (P = .017) in leiomyoma patients, whereas HCT and RBC values were not significantly different between the 2 groups.

Conclusion: The RDW-CV, PLT and PCT values were significantly higher in leiomyoma patients, whereas WBC, RBC, MPV, PDW, P-LCR, NLR, PLR were not significantly different. Still, the specificity of RDW-CV, PLT and PCT was not high enough to allow using them as diagnostic tools for leiomyoma.

Item Type: Article
Subjects: STM Open Press > Medical Science
Depositing User: Unnamed user with email support@stmopenpress.com
Date Deposited: 20 Feb 2023 08:57
Last Modified: 01 Aug 2024 08:37
URI: http://journal.submissionpages.com/id/eprint/438

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