Distribution and Antimicrobial Susceptibility Profile of Bacterial Isolates in Males and Non- pregnant Females with Urinary Tract Infection in University of Benin Health Centre, Nigeria

Urinary tract infections (UTIs) have become the most common hospital and community acquired infections resulting in high morbidity. The prevalence of bacteria causing UTI as well as their susceptibility to commonly used antibiotics was investigated at the University of Benin Health Centre (UBHC), Benin city, Nigeria. Bacterial species isolated from the urine samples analyzed were Escherichia coli, Klebsiella sp. Enterococcus sp., Staphylococcus aureus, Proteus mirabilis and Pseudomonas aeruginosa. UTIs in this study, was found to be more prevalence in females (60% for 15- 26 years and 53% for 27- 32 years) than in males (40% for 15- 26 years and 47% for 27-32 years). The isolates were identified by carrying out standard biochemical tests and comparing with characteristics of known taxa. Susceptibility tests were performed by Bauer-Kirby Disc diffusion method with eleven antibiotics. The results were expressed as susceptible ̸̸ resistant. Gram-negative isolates had a prevalence of 66.7%, while Gram-positive isolates had 33.3%. E. coli were found to be the most prevalence occurring in 80% of the samples, while the least prevalent were Pseudomonas aeruginosa. Staphylococcus sp and Enterococcus sp occurred in 40% of the samples. All isolates were found to be susceptible to ciprofloxacin. Gram-positive isolates were 100% resistant to Penicillin, while the Gram-negative isolates were 100% resistant to Amikacin.